Unité de Recherche Clinique Sommeil et Neuropsychopharmacologie
Directeur de recherche : Dr Luc Staner
Intitulé de l’équipe : Unité de Recherche Clinique Sommeil et Neuropsychopharmacologie
Rattachement (EPST, INSERM, CNRS) : Centre Hospitalier de Rouffach et Forenap R&D
Directeur de recherche : STANER LUC
Adresse de l’équipe de recherche : 27 rue du 4 RSM, F-68250 Rouffach
Thèmes de recherche :
1° Neuropsychopharmacologie du sommeil
2° Insomnie
3° Emotions, mémoire et sommeil
Travaux en cours :
1° Modèles d’insomnie chez le sujet sain
2° Privation partielle de sommeil et régulation émotionnelle
3° Utilisation de biomarqueurs sommeil en médecine translationnelle
4° Mélatonine et trouble dépressif
Publications des 3 dernières années (en rouge les publications se rapportant à des travaux réalisés en partie ou totalement in situ par l’équipe de recherche)
2010
• Al-Shamma HA, Anderson C, Chuang E, Luthringer R, Grottick AJ, Hauser E, Morgan M, Shanahan W, Teegarden BR, Thomsen WJ, Behan D.Nelotanserin, a Novel Selective Human 5-Hydroxytryptamine2A inverse Agonist for the Treatment of Insomnia. J Pharmacol Exp Ther. 2010 ;332:281-290.
• Staner L. Comorbidity of insomnia and depression. Sleep Med Rev 2010 ;14:35-46.
• Tassi P, Saremi M, Schimchowitsch S, Eschenlauer A, Rohmer O, Muzet A. Cardiovascular responses to railway noise during sleep in young and middle-aged adults. Eur J Appl Physiol. 2010 Mar ;108(4):671-80.
2009
• Le Bon O, Hoffmann R, Staner L, Armitage R. Relationships between the number of ultradian cycles and key sleep variables in outpatients with major depressive disorder. Psychiatry Res. 2009 Jan 30 ;165(1-2):60-67.
• Luthringer R, Muzet M, Zisapel N, Staner L. The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia. International Clinical Psychopharmacology. 2009 Sep ; 24(5):239-49.
• Mayer G, Wang-Weigand S, Roth-Schechter B, Lehmann R, Staner C, Partinen M. Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia. Sleep. 2009 Mar 1 ;32(3):351-60.
• Muzet A. Un sommeil perturbé : les répercussions d’une exposition répétée au bruit ambiant. Concours Med 2009 ;131 :229-231.
• Muzet A. Insomnie due aux facteurs environnementaux. Archives des maladies professionnelles et de l’environnement 2009 ; 70:300-305.
• Roge J, Otmani S, Bonnefond A, Depayle T, Muzet A. Effect of a short nap on the alertness of young drivers : Repercussion on the perception of motorcycles according to extent of the useful visual field of the driver. Transportation Research Part F. 2009 ; 12:143-154.
• Staner L, Eriksson M, Cornette F, Santoro F, Muscat N, Luthinger R, Roth T. Sublingual zolpidem is more effective than oral zolpidem in initiating early onset of sleep in the post-nap model of transient insomnia : a polysomnographic study. Sleep Medicine 2009 ;10:616-620.
2008
• Bonnefond A, Saremi M, Rohmer O, Hoeft A, Eschenlauer A, Eschenlauer R, Muzet A, Tassi P. Effects of nocturnal railway noise on subsequent cognitive performance and subjective ratings. Somnologie 2008 ; 12(2) : 130-138.
• Grenèche J, Krieger J, Erhardt C, Bonnefond A, Eschenlauer A, Muzet A, Tassi P. EEG spectral power and sleepiness during 24 h of sustained wakefulness in patients with obstructive sleep apnea syndrome.Clin Neurophysiol 2008 ;119 :418-428.
• Grenèche J, Sarémi M, Erhardt C, Hoeft A, Eschenlauer A, Muzet A, Tassi P. Severity of obstructive sleep apnoea/hypopnoea syndrome and subsequent waking EEG spectral power. Eur Respir J 2008 ;32:705-709.
• Muzet A. Les perturbations du sommeil par les facteurs physiques de l’environnement et leurs répercussions sur la vie quotidienne. Médecine du Sommeil 2008 ;18:5-9.
• Otmani S, Demazières A, Staner C, Jacob N, Nir T, Zisapel N, Staner L. Effects of prolonged-release melatonin, zolpidem, and their combination on psychomotor functions, memory recall, and driving skills in healthy middle aged and elderly volunteers. Hum Psychopharmacol Clin Exp. 2008 ; 23(8):693-705.
• Saremi M, Rohmer O, Burgmeier A, Bonnefond A, Muzet A, Tassi P. Combined effects of noise and shiftwork on fatigue as a function of age. International Journal of Occupational Safety and Ergonomics. 2008 ; 14(4):387-94.
• Tassi P, Grenèche J, Pebayle T, Eschenlauer A, Hoeft A, Bonnefond A, Rohmer O, Muzet A. Are OSAS patients impaired in their driving ability on a circuit with medium traffic density ? Accident Analysis and Prevention 2008 ;40:1365–1370.
2007 • Chouvarda I, Papadelis C, Domis N, Staner L, Maglaveras N. Insomnia treatment assessment based on physiological data analysis. Conf Proc IEEE Eng Med Biol Soc. 2007 ;2007:6695-6697.
• Deacon S, Staner L, Staner C, Legters A, Loft H, Lundahl J. Effect of short-term treatment with gaboxadol on sleep maintenance and initiation in patients with primary insomnia. Sleep 2007 ;30(3):281-287.
• Lundahl J, Staner L, Staner C, Loft H, Deacon S. Short treatment with Gaboxadol improves sleep maintenace and enhances slow wave sleep in adult patients with primary insomnia. Psychopharmacology 2007 ;195:139-146.
• Luthringer R, Staner L, Noel N, Muzet M, Gassmann-Mayer C, Talluri K, Cleton A, Eerdekens M, Battisti WP, Palumbo JM. A double-blind, placebo-controlled, randomized study evaluating the effect of paliperidone extended release tablets on sleep architecture in patients with schizophrenia. Int Clin Psychopharmacol 2007 ; 22(5):299-308.
• Muzet A. Environmental noise, sleep and health. Sleep Medicine Reviews 2007 ;11:135-142.>
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