Directeur de recherche : Pr Pierre PHILIP
Intitulé de l’équipe : GENPPHASS
Rattachement (EPST, INSERM, CNRS) : UMR CNRS 5227
Directeur de recherche : Professeur Pierre PHILP
Adresse de l’équipe de recherche : Plateforme de recherche Neuro-Psychopharmacologique
Hôpital Pellegrin
Tripode 13ème Etage
Place Amélie Raba Léon
33076 BORDEAUX CEDEX
Thèmes de recherche : Sommeil, attention, performances neurocognitives
Vieillissement, TDAH, hypersomnie
Dépression, addiction et troubles du sommeil
Travaux en cours :
– Contre-mesures à la somnolence
– Narcolepsie : impact des traitements dans l’aptitude à la conduite
– Vieillissement, Homéostasie et rythmes circadiens en constant routine
– TDAH, somnolence et conduite automobile
– Benzodiazépines, cannabis et aptitude à la conduite
Publications des 3 dernières années :
2009
1. Léger D., Philip P., Jarriault P., Metlaine M., Choudat D. Effects of a combinaison of napping and bright light pulses on shift workers sleepiness at the wheel : a pilot study. Journal of Sleep Research, 2009, 18 (4) : 472-479.
2. Bayon V., Léger D., Philip P. Socio-professional handicap and accidental risk in patients with Hypersomnias of Central Origin. Sleep Medicine Review, 2009, 13 (6) : 421-426.
3. Stoohs R.A., Philip P., Andries D., Finlayson E.V.A., Guilleminault C. Reaction time performance in upper airway resistance syndrome versus obstructive sleep apnea syndrome. Sleep Medicine, 2009, 10(9) : 1000-1004.
4. Niedhammer I., David S., Degioanni S., Drummond A., Philip P., and 143 occupational physicians. Workplace bullying and sleep disturbances : findings from a large scale cross-sectional survey in the French working population. Sleep, 2009, 32 (9) :1211-1219.
5. Farid K., Jeannin S., Lambrecq V., Philip P., Fernandez P., Molinier S., Allard M., Sibon S. Paraneoplastic cataplexy : clinical presentation and imaging findings in a case. Movement Disorders, 2009, 24 (12) : 1854-1856.
6. Pépin J.L., Muir J.F., Gentina T., Dauvilliers Y, Tamisier R., Sapene M., Escourrou P., Fleury B., Philip-Joet F., Philip P., d’Ortho M.P. Pressure reduction during exhalation in sleep apnea patients treated by Continuous Positive Airway Pressure. Chest, 2009, 136 (2) :490-497.
7. Orriols L., Salmi L.R., Philip P., Moore N., Delorme B., Castot A., Lagarde E. The impact of medicinal drugs on traffic safety : a systematic review of epidemiological studies. Pharmacoepidemiol Drug Saf, 2009, 18 (8) :647-658.
8. Chaumet G., Taillard J., Sagaspe P., Pagani M., Dinges D.F., Pavy-Le-Traon A., Bareille M.P., Rascol O., Philip P. Confinement and sleep deprivation effects on propensity to take risks. Aviation Space and Environmental Medicine, 2009, 80 (2) : 73-80.
9. Pagani M., Pizzinelli P., Pavy-Le Traon A.,Ferreri C., Beltrami S., Bareille M.P., Costes-Salon M.C., Béroud S., Blin O., Lucini D., Philip P. Hemodynamic, autonomic and baroreflex changes after one night sleep deprivation in healthy volunteers. Autonomic Neuroscience : Basic and Clinical, 2009, 145 : 76-80.
2008 10. Chaumet G., Quera-Salva M.A., MacLeod A., Hartley S., Taillard J., Sagaspe P., Mazaux J.M., Azouvi P., Joseph P.A., Guilleminault C., Bioulac B., Léger D., Philip P. Is there a link between alertness and fatigue in patients with traumatic brain injury ? Neurology, 2008, 71 : 1609-1613.
11. Philip P., Sagaspe P., Taillard J., Chaumet G., Bayon V., Coste O., Bioulac B., Guilleminault C. Maintenance of wakefulness test, obstructive sleep apnea syndrome and driving risk. Annals of Neurology, 2008, 64 : 410-416.
12. Sagaspe P., Taillard J., Akerstedt T., Bayon V., Espié S., Chaumet G., Bioulac B., Philip P. Extended driving impairs nocturnal driving performances. PLOS ONE, 2008, 3 (10) : e3493.
13. Vecchierini M.F., Léger D., Laaban J.P., Putterman G., Figueredo M., Levy J., Vacher C., Monteyrol P.J., Philip P. Efficacy and compliance of mandibular repositioning device in obstructive sleep apnea syndrome under a patient-driven protocol of care. Sleep Medicine, 2008, 9 (7) : 762-769.
14. Galliaud E., Taillard J., Sagaspe P., Valtat C., Bioulac B, Philip P. Sharp and sleepy : evidence for dissociation between sleep pressure and nocturnal performance. Journal of Sleep Research, 2008, 17 : 11-15.
2007 15. Sagaspe P., Taillard J., Chaumet G., Moore N., Bioulac B, Philip P. Aging and Nocturnal Driving : Better with a Coffee or a Nap ? A Randomized Study. Sleep, 2007, 30 (12) : 1808-1813.
16. Sagaspe P., Philip P. , Schwartz S. Inhibitory Motor Control in Apneic and Insomniac Patients : A Stop Task Study. Journal of Sleep Research, 2007, 16 : 381-387.
17. Sagaspe P., Taillard J., Chaumet G., Guilleminault C., Coste O., Moore N., Bioulac B, Philip P. Maintenance of wakefulness test as a predictor of driving performance in patients with untreated obstructive sleep apnea. Sleep, 2007, 30 (3) : 327-330.
18. Constans J., Germain C., Gosse P., Taillard J., Tiev K., Delevaux I., Mouthon L., Schmidt C., Granel F., Soria P., Lifermann F., Etienne G., Bonnet F., Zoulim K., Farge-Bancel D., Marie I., Allanore Y., Cabane J., Amonchot A., Macquin-Mavier I., Saves M., Zannad F., Conri C., the ERAMS investigators. Arterial stiffness predicts severe progression in systemic sclerosis : the ERAMS study. Journal of Hypertension, 2007, 25 :1900–1906.
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